MMOMinion

For Example:
Copper ingot requires 3 Copper Ore.
I want to use 2 HQ Copper Ore and 1 NQ Copper Ore

It that possible?

if you only have 2 HQ left yes but if you have a stack of hQ no.

Any update on this?
I want to craft using some HQ and some normal version of the same mat

The only way that I've found for the bot to do this, which sucks cause you have to do it for each synth, is to set your mats up, hit the craft button on the game, then once the craft starts, hit start on the bot and let the skill profile finish the synth. You will have to stop the bot as the synth completes, or it will take over and use all/none of the hq mats again.