[AzRed]

Ran VA today at last boss; the profile just went to spam mutilate/shadowfang. Tried reloading the bot and the problem still persisted. I'll continue to observe for now

I'm getting exact same problem, keep spamming shadowfang / multilate :(

If I may - this is a common issue that stems from how FFXIV stores dots on mobs and in memory. There is a cap to the number of status effects that will show up client side. While the dots may be on the enemies, if the number of status effects surpasses this threshold the will not be written into client memory and only be handled server side. If your characters dots are something that show up on the boss after this limit is reached, there will be no way for Minion to monitor the remaining time on these dots and will see them as not applied and try to reapply. 

This is something that has happened since day one and, unless Square decides to transmit ALL boss status effects to client side for display you're going to have to deal with, regardless of the profile in use.